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What does RAMP3 stand for?

RAMP3 receptor activity modifying protein 3 [ (human)] The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.

What is the topology of RAMP3?

A RAMP Structure RAMP1, RAMP2, and RAMP3 share a common topology consisting of a large extracellular amino-terminus, a single transmembrane (TM) segment and a small intracellular C-terminus.

What diseases are associated with the RAMP3 gene?

Diseases associated with RAMP3 include Cartilage Cancer and Chronic Monocytic Leukemia . Among its related pathways are Presynaptic function of Kainate receptors and Myometrial Relaxation and Contraction Pathways . Gene Ontology (GO) annotations related to this gene include signaling receptor activity and coreceptor activity .

What is RAMP1 and RAMP2?

RAMP1 is widely expressed in the brain, spinal cord, gastrointestinal tract, adrenal gland, perivascular nerve, and smooth muscles of the arteries. RAMP2 is found in macrovascular and microvascular endothelial cells, vascular smooth muscle, and cardiomyocytes.


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